Abstract: With the continuous development of modern industry, the integrated turbine compressor, as a new type of equipment with energy-saving, efficient, and reliable characteristics, has shown broad application prospects.However, there is no mature control mode for the design and implementation of the control and protection system of the integrated turbine compressor.In order to achieve efficient, stable, and safe operation of the integrated turbine compressor, this article conducts research on the design of its control and protection system.The article proposes the application of programmable logic controller(PLC) in the system and elaborates on the specific application of PLC in system hardware and software design.Research has shown that PLC can achieve real-time monitoring and process control optimization of the operating status of the turbine compression integrated machine, ensuring reliable, flexible, and efficient operation of the system.This study fully demonstrates the important role of PLC in the design and implementation of the control and protection system for the integrated turbine compressor, providing important references for the further development and application of this equipment.