Abstract: In this paper, based on a radial-flow impeller structure, the finite element numerical calculation model of the impeller is established, and the accuracy of the calculation results is verified through experiments.The influence of the impeller natural frequency is analyzed by blade thickness, disc thickness, and disc groove angle.The calculation results show that the natural frequency of the impeller blade can be adjusted by changing the blade thickness.There is a linear relationship between the disc thickness, the disc groove angle, and the first-order natural frequency of the impeller.But the linear slope laws of different pitch diameters are different, which provides a method for frequency modulation of the impeller disc vibration in the future.However, the linear slope laws of different nodal diameter numbers are different, which provides a method for frequency modulation of the impeller disc vibration in the future.Comparing the vibration analysis results of the independent impeller model and the impeller-rotor assembly model, it is shown that the analysis with rotor has an effect on the natural frequency of the impeller disk vibration at low nodal diameter.