Abstract: In the burgeoning field of nuclear power equipment manufacturing, the advent of digital factories heralds a transformative era, leveraging the prowess of IPv6 technology to revolutionize network infrastructure.This study delves into the intricacies of designing an IPv6 network tailored for the digitalization of nuclear power equipment factories, encapsulating a blend of technological innovation and strategic foresight.The research commences with an exploration of the historical trajectory and current landscape of digital factories within the nuclear sector, underscoring the imperative for a robust, scalable, and secure network framework.IPv6,with its expansive address space and enhanced security features, emerges as a cornerstone in this architectural endeavor.The methodology encompasses a meticulous analysis of network architecture, security protocols, and management strategies, enriched with detailed case studies from leading nuclear equipment manufacturers.These case studies illuminate the practical implementation and operational nuances of IPv6 networks, offering a nuanced perspective on their efficacy and challenges.The findings reveal a promising trajectory for IPv6 integration, promising not only enhanced connectivity and security but also paving the way for future innovations in smart manufacturing.As the nuclear industry strides towards a more interconnected and intelligent future, the role of IPv6 in shaping this evolution is both profound and indispensable.